* = Human studies with bovine colostrum
O = Studies directly related to bovine colostrum
O 105.

Wada et. al., 1980, Infection and Immunity, 29, pp 545-550. "Neutralizing Activity Against Clostridium Difficile Toxins in the Supernatants of Cultured Colostral Cells": Colostrum immune factors neutralize crude toxins

O 106.

Paulik, et. al., 1985, Veterinari Medicina, Poland, Vol. 30 No 1 pp. 21-28: " Lysozyme in the Colostrum and Blood of Calves of Diary Cows": Lysoszyme in bovine (and human) colostrum is the enzyme present in egg white, tears, saliva and other body fluids that kills bacteria by dissolving their cell walls.

O 107.

Tokuyama and Tokuyama, 1989, Dept. of Molecular Immunology, Cancer Research Institute and Dept. of Nuclear Medicine, Kananawa University, Kanaawa, Japan. Harwood Academic Publishers, UK. Cellular Biology Report 13, 251-258; "Bovine Colostric Transforming Growth Factor-B-Like peptide induces growth inhibition and changes morphology of human osteogenic sarcoma (cancer) cells": TgF B produced cell destruction in certain human cancer (sarcoma) cells in cell culture growth experiments in Japan.

O 108.

Tokuyama, et. al., 1990, Dept. of Molecular Immunology, Cancer Research Institute and Dept. of Nuclear Medicine, Kananawa University, Kanaawa, Japan. Harwood Academic Publishers, UK: Reported two new Proteins discovered in Bovine Colostrum: BC-1 and BC-2. Belong to a new class of mitogen inhibitors. Reported that through biological activities resemble TGF-B. Showed inhibitory effect on some sarcoma (cancer) tumor cell lines in sutro.

O 109.

Dillehay, Dirck L. American Institute of Nutrition. 1994. Biochemical and Molecular Roles of Nutrients. Dietary Sphingomyelin (Found in bovine colostrum and milk) Inhibits 1,2-Dimethylhydrazine-Induced Colon Cancer in CF1 Mice1-4. Sphingomyelin significantly reduced evidence of colon cancer.

O 110.

Parodi, PW. The Australian Journal of Dairy Technology, Vol. 51, April 1996. Bovine milk fat components: possible chemopreventive agents for cancer and other diseases. Evidence suggests that bovine milk fat contains cancer fighting components.

O 111.

Neely, EK, et al, Dept. of Ped., Stanford Univ. Sch. Of Med., Calif., J. Invest. Dermatol., 1991. "Insulin-like growth factors are mitogenic for human keratinocytes and a squamous cell carcinoma."


Moro, et. al., 1985, Cellular Immunology, 93(2) pp. 467-74: "Natural Killer Cells in Human Colostrum": Approximately 0.5% of colostral cells were identified as natural killer cells of two morphological types.


Tokuyama and Tokuyama, 1993, Jour.Dairy Res. Vol 60: 99-109 (Printed in Great Britain) Bovine colostrum contains high levels of transforming growth factor (TGF) - beta-like activity during the first 12 30 hours after parturition. Results of study indicate that TGF-beta-like growth factor found in bovine colostrum is chemically and antigenically related to TGF-beta2.


Hakansson, et. al., Proceedings, the Nation Academy of the Sciences, Vol 92, pp. 8064-8068 Aug. 1995, Research Study: Lund University, Stockholm, Sweden. Study showed in vitro effect of ingredient in human milk and colostrum: multimeric a-lactalbumin caused lung cancer (transformed epithelial cells) to create selective suicide. (apatosis). Normal surrounding cells unaffected. Conclusion: multimeric a-lactalbumin - is a potent Ca2+ -elevating and apoptosis-inducing agent with broad, yet selective, cytoxic activity.


Business Week, Feb. 6, 1995: "Quiet Strides in the War on Cancer": National Cancer Institute researcher Steven A. Rosenberg became a media sensation when he achieved success with cancer patients in 1985 using an experimental technique called immunotherapy. Since cancers can invade the immune system, why not load the body with killer immune cells, along with special chemical messengers called Cytokines that give the body an extra kick." Treatments partially successful. More trials ongoing. Cytokine for cancer vaccines is the largest single protocol under study today.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent disease.